That's certainly your choice - however, have you tried braid before? I don't have any problems tying knots...and that would be especially true with heavier (50lb or more) braid. I turned to braid for all my fishing 5 years ago from freshwater trout and bass, to the 'big' four here in NE (stripers, blues, bonito, albies)...as well as whatever groundfishing I still do (from party boats and my yak). Someone would have to outlaw it before I switched back. There's no way mono is better than braid.
There are probably certain applications where mono might be more appropriate. However, those are far and few between (and generally freshwater orientated)...and braid will still suffice in those situations. In deepwater fishing for fish such as cod and haddock (regardless of bait or jigging) braid is way more advantageous than mono...no stretch, more sensitive, more power to drive the hook home. If you're that worried about knots, you could easily tie on a clip to the end of the braid while you're still at home (as well as some pre-tied rigs with both bait and jigging set ups)...that way, all you have to do is clip on a new pretied rig if so necessary.